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Angiogenin Antibodies
AND ANG ELISA kits, Angiogenin Proteins
Many biological assays use antibodies to detect Angiogenin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Angiogenin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Angiogenin antibodies...
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ANG Infographic by Boster Bio
All ANG Products
Product
Figures
Specificity
Applications
Price
Human Angiogenin/ANG ELISA Kit PicoKine®
6 Citations 8 Q&As
Human
ELISA
$499
Cat # EK0305
96 wells/kit, with removable strips.
Cat # EK0305
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00146
100 μg/vial
Cat # A00146
100 μg/vial
Human
ELISA
$500
Cat # EZ0305
For 5 plates, 96 wells each
Cat # EZ0305
For 5 plates, 96 wells each
Human
ELISA
$499
Cat # FEK0305
96 wells/kit, with removable strips.
Cat # FEK0305
96 wells/kit, with removable strips.
ANG Overview
Facts about Angiogenin.
Angiogenin (ANG)
Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA.
Cleaves tRNA within anticodon loops to generate tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues.
Gene Information
| Human | |
|---|---|
| Gene Name: | ANG |
| Uniprot: | P03950 |
| Entrez: | 283 |
Family
| Belongs to: |
|---|
| pancreatic ribonuclease family |
Alternative Names
ALS9; ANG; Angiogenin; angiogenin, ribonuclease, RNase A family, 5; EC 3.1.27; EC 3.1.27.-; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; Ribonuclease 5; RNase 5; RNASE5RNASE4
Molecular Weight
Mass (kDA):
16.55 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q11.2 |
| Sequence: | 14; NC_000014.9 (20684177..20694186) |
Tissue Specificity
Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons.
Subcellular Localizations
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus. Nucleus, nucleolus. Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (PubMed:12051708).
Diseases
- Hypertensive Disease
- Hypertrophy
- Pathologic Vasoconstriction
- Fibrosis
- Kidney Diseases
- Heart Failure
- Inflammation
- Cardiovascular Diseases
- Cardiac Hypertrophy
- Diabetes Mellitus
- Atherosclerosis
- Disease Of Adrenal Medulla
- Tumor Angiogenesis
Interacting Proteins
- ACTN2
- ANXA2
- FST
- PCNA
- PLAUR
- RNH1
- S100A10
Pathways
- Secretion
- Excretion
- Vasoconstriction
- Pathogenesis
- Glomerular Filtration
- Angiogenesis
- Cell Proliferation
- Localization
- Cell Growth
- Transport
- Vasodilation
- Reflex
- Natriuresis
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Reduction
- Dephosphorylation
- Nitration
- Glycosylation
- Acetylation
- Iodination
- Myristoylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANG
bosterbio.com/bosterbio-gene-info-cards/ANG
References
PMID: 2866795 by Kurachi K., et al. Sequence of the cDNA and gene for angiogenin, a human angiogenesis factor.
PMID: 11919285 by Zhang J., et al. Diversifying selection of the tumor-growth promoter angiogenin in primate evolution.
6 Publications of Boster Angiogenin Antibodies & ELISA Kits
- PubMed ID: 10.14744/AnatolJCardiol.2019.88555, The association between serum angiogenin and osteopontin levels and coronary col...
- PubMed ID: 20043346, Cytocompatibility of regenerated silk fibroin film: a medical biomaterial applic...
- PubMed ID: 2801084, Cytocompatibility of regenerated silk fibroin film: a medical biomaterial applic...
- PubMed ID: 24040410, Li C, Fan J, Song X, Zhang B, Chen Y, Li C, Mi K, Ma H, Song Y, Tao X, Li G. Plo...
- PubMed ID: 25564450, Shi H, Zhang Y, Fu S, Lu Z, Ye W, Xiao Y. Invest Ophthalmol Vis Sci. 2015 Jan 6;...
- PubMed ID: 24759991, Bai X, Li X, Tian J, Zhou Z. Plos One. 2014 Apr 23;9(4):E96117. Doi: 10.1371/Jou...
*More publications can be found for each product on its corresponding product page