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- Table of Contents
Facts about Calcium-transporting ATPase type 2C member 1.
Human | |
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Gene Name: | ATP2C1 |
Uniprot: | P98194 |
Entrez: | 27032 |
Belongs to: |
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cation transport ATPase (P-type) (TC 3.A.3) family |
ATPase, Ca++ transporting, type 2C, member 1; BCPM; benign chronic pemphigus (Hailey-Hailey disease); Ca(2+)-sequestering; calcium-transporting ATPase type 2C member 1; EC 3.6.3; HHD; hSPCA1; HUSSY-28; PMR1L; secretory pathway Ca2+/Mn2+ ATPase 1
Mass (kDA):
100.577 kDA
Human | |
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Location: | 3q22.1 |
Sequence: | 3; NC_000003.12 (130850595..131016712) |
Found in most tissues except colon, thymus, spleen and leukocytes. Most abundant in keratinocytes and kidney.
Golgi apparatus membrane; Multi-pass membrane protein.
PMID: 10615129 by Hu Z., et al. Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.
PMID: 10767338 by Sudbrak R., et al. Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump.