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Product Info Summary
| SKU: | A09984-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-ZNF346 (CT) Antibody
SKU/Catalog Number
A09984-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ZNF346 (CT) Antibody (Catalog # A09984-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
ZNF346 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ZNF346 (CT) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09984-1)
Host
Rabbit
Contents
ZNF346 (CT) Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZNF346 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human ZNF346. The immunogen is located within the last 50 amino acids of ZNF346.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ZNF346 antibody is predicted to not cross-react with other ZNF family members. Three isoforms of ZNF346 are known to exist; this antibody will recognize the two longest isoforms
Reactive Species
A09984-1 is reactive to ZNF346 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
32933 MW
Background of ZNF346
ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09984-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZNF346 antibody can be used for detection of ZNF346 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZNF346 in human kidney tissue lysate with ZNF346 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of ZNF346 (CT) in human kidney tissue with ZNF346 (CT) antibody at 5 μg/mL.
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Immunofluorescence of ZNF346 in human kidney tissue with ZNF346 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ZNF346 (Source: Uniprot.org, NCBI)
Gene Name
ZNF346
Full Name
Zinc finger protein 346
Weight
32933 MW
Alternative Names
JAZ, Zfp346, JAZ, Zinc finger protein 346, Just another zinc finger protein ZNF346 JAZ, Zfp346 zinc finger protein 346 zinc finger protein 346|double-stranded RNA-binding zinc finger protein JAZ|just another zinc finger protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ZNF346, check out the ZNF346 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ZNF346: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ZNF346 (CT) Antibody (A09984-1)
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