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Product Info Summary
| SKU: | A09987 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-ZIMP7 ZMIZ2 Antibody
SKU/Catalog Number
A09987
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ZIMP7 ZMIZ2 Antibody (Catalog # A09987). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
ZIMP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ZIMP7 ZMIZ2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09987)
Host
Rabbit
Contents
ZIMP7 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZIMP7 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIMP7. The immunogen is located within amino acids 270 - 320 of ZIMP7.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.
Reactive Species
A09987 is reactive to ZMIZ2 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
96537 MW
Background of Zmiz2
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09987 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZIMP7 antibody can be used for detection of ZIMP7 by Western blot at 0.25 - 0.5 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZIMP7 in A20 cell lysate with ZIMP7 antibody at (A) 0.25 μg/ml and (B) 0.5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ZMIZ2 (Source: Uniprot.org, NCBI)
Gene Name
ZMIZ2
Full Name
Zinc finger MIZ domain-containing protein 2
Weight
96537 MW
Alternative Names
NET27, ZIMP7, hZIMP7, TRAFIP20, KIAA1886, HRIHFB2007, Zinc finger MIZ domain-containing protein 2, PIAS-like protein Zimp7 Zmiz2|Zim, Zimp7|zinc finger, MIZ-type containing 2|zinc finger MIZ domain-containing protein 2|PIAS-like protein Zimp7
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ZMIZ2, check out the ZMIZ2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ZMIZ2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ZIMP7 ZMIZ2 Antibody (A09987)
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