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Product Info Summary
| SKU: | M02855 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | WB |
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Product info
Product Name
Anti-XRN1 Antibody
SKU/Catalog Number
M02855
Size
50 µl
Description
Boster Bio Anti-XRN1 Antibody (Catalog # M02855). Tested in WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-XRN1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02855)
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
1647CT536.85.48
Isotype
IgG1,k
Immunogen
This XRN1 antibody is generated from a mouse immunized with arecombinant protein between1455-1706 amino acids from human XRN1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M02855 is reactive to XRN1 in Human
Reconstitution
Calculated molecular weight
194107 Da
Background of Xrn1
Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M02855 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000
Validation Images & Assay Conditions
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All lanes : Anti-XRN1 Antibody at 1:2000 dilution
Lane 1: K562 whole cell lysate
Lane 2: MCF-7 whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 194 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For XRN1 (Source: Uniprot.org, NCBI)
Gene Name
XRN1
Full Name
5'-3' exoribonuclease 1
Weight
194107 Da
Superfamily
5'-3' exonuclease family
Alternative Names
5'-3' exoribonuclease 1, 3.1.13.-, Strand-exchange protein 1 homolog, XRN1, SEP1 Xrn1|Dhm2, exo, mXr, mXrn1|5-3 exoribonuclease 1|5-3 exoribonuclease 1|protein Dhm2|strand-exchange protein 1 homolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on XRN1, check out the XRN1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for XRN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-XRN1 Antibody (M02855)
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No publications found for M02855
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