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- Table of Contents
Facts about 5'-3' exoribonuclease 1.
The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds into RNA and DNA.
Mouse | |
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Gene Name: | Xrn1 |
Uniprot: | P97789 |
Entrez: | 24127 |
Belongs to: |
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5'-3' exonuclease family |
5'-3' exoribonuclease 1; DKFZp434P0721; DKFZp686B22225; DKFZp686F19113; EC 3.1.11.-; SEP1FLJ41903; Strand-exchange protein 1 homolog
Mass (kDA):
194.307 kDA
Mouse | |
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Location: | 9|9 E3.3 |
Sequence: | 9; |
Expressed in heart, brain (spinal cord, dorsal root and superior cervical ganglia, neurons of the cerebrum and brain stem), peripheral nerve fibers in the skin and intestine, spleen, lung, liver, skeletal muscle, kidney and testis.
PMID: 9218715 by Shobuike T., et al. Cloning and characterization of mouse Dhm2 cDNA, a functional homolog of budding yeast SEP1.
PMID: 9049243 by Bashkirov V.I., et al. A mouse cytoplasmic exoribonuclease (mXRN1) with preference for G4 tetraplex substrates.