Anti-DNA repair protein XRCC2 XRCC2 Antibody

Product Name

Anti-DNA repair protein XRCC2 XRCC2 Antibody

View all XRCC2 Antibodies

SKU/Catalog Number

A02138

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-DNA repair protein XRCC2 XRCC2 Antibody (Catalog # A02138). Tested in WB, IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DNA repair protein XRCC2 XRCC2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02138)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human XRCC2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02138 is reactive to XRCC2 in Human

Reconstitution

Calculated molecular weight

31956 MW

Background of XRCC2

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.

JP Scott, Blood, Oct 1981; 58: 665 - 669.
G Chevalier, Am. J. Pathol., Jun 1998; 152: 1563.
R Williams, J. Biol. Chem., Aug 1993; 268: 18213 - 18217.
Michael R. Ladomery, J. Biol. Chem., Dec 1999; 274: 36520.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A02138 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

Gene/Protein Information For XRCC2 (Source: Uniprot.org, NCBI)

Alternative Names

DNA repair protein XRCC2;X-ray repair cross-complementing protein 2;XRCC2; XRCC2 FANCU, POF17, SPGF50 X-ray repair cross complementing 2 DNA repair protein XRCC2|X-ray repair complementing defective repair in Chinese hamster cells 2|X-ray repair cross-complementing protein 2|epididymis secretory sperm binding protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis