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Product Info Summary
| SKU: | A12524 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-WDR61 Antibody
SKU/Catalog Number
A12524
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-WDR61 Antibody (Catalog # A12524). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
WDR61 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-WDR61 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12524)
Host
Rabbit
Contents
WDR61 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
WDR61 antibody was raised against a 14 amino acid peptide near the amino terminus of human WDR61. The immunogen is located within the first 50 amino acids of WDR61.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
WDR61 antibody is human, mouse and rat reactive.
Reactive Species
A12524 is reactive to WDR61 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
33581 MW
Background of Wdr61
WDR61 (WD-repeat-containing protein 61), also known as SKI8 or REC14, is a subunit of the human PAF and SKI complexes, which function in transcriptional regulation and are involved in events downstream of RNA synthesis, such as RNA surveillance (1,2). PAF1C is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1C (3,4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12524 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WDR61 antibody can be used for detection of WDR61 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of WDR61 in SK-N-SH cell lysate with WDR61 antibody at 1 μg/ml.
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Immunohistochemistry of WDR61 in mouse brain tissue with WDR61 antibody at 5 μg/ml.
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Immunofluorescence of WDR61 in mouse brain tissue with WDR61 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For WDR61 (Source: Uniprot.org, NCBI)
Gene Name
WDR61
Full Name
WD repeat-containing protein 61
Weight
33581 MW
Alternative Names
WD repeat-containing protein 61, Meiotic recombination REC14 protein homolog, REC14, SKI8
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on WDR61, check out the WDR61 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for WDR61: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-WDR61 Antibody (A12524)
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