Anti-VNN3 Antibody

Product Name

Anti-VNN3 Antibody

View all Vnn3 Antibodies

SKU/Catalog Number

A10601

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-VNN3 Antibody (Catalog # A10601). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

VNN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-VNN3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10601)

Host

Rabbit

Contents

VNN3 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

VNN3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human VNN3. The immunogen is located within the last 50 amino acids of VNN3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Multiple isoforms of VNN3 are known to exist.

Reactive Species

A10601 is reactive to Vnn3 in Human, Mouse, Rat

Applications

A10601 is guaranteed for ELISA, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

56118 MW

Background of Vnn3

The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

VNN3 antibody can be used for detection of VNN3 by Western blot at 0.5 and 1 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

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Western blot analysis of VNN3 in human brain tissue lysate with VNN3 antibody at (A) 0.5 and (B) 1 μg/mL.

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Immunohistochemistry of VNN3 in human liver tissue with VNN3 antibody at 5 μg/mL.

Gene/Protein Information For Vnn3 (Source: Uniprot.org, NCBI)

Alternative Names

HSA238982; MGC171203; vanin 3

For more info on Vnn3, check out the Vnn3 Infographic

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In this infographic, you will see the following information for Vnn3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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