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Product Info Summary
| SKU: | A00326 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Tyrosinase Antibody
View all Tyrosinase Antibodies
SKU/Catalog Number
A00326
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Tyrosinase Antibody (Catalog # A00326). Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Tyrosinase Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00326)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human tyrosinase.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00326 is reactive to TYR in Human
Reconstitution
Calculated molecular weight
60393 MW
Background of Tyrosinase
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
Patricia Giraldo, Nucleic Acids Res., Nov 2003; 31: 6290 - 6305.
R Halaban, J. Cell Biol., Aug 1983; 97: 480.
Hee-Young Park, J. Biol. Chem., Jun 1999; 274: 16470.
BB Fuller, J. Biol. Chem., Mar 1987; 262: 4024 - 4033.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00326 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
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Western blot analysis of extracts from HepG2 cells (Lane 2), using Tyrosinase antiobdy A00326. The lane on the left is treated with synthesized peptide.
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Western blot analysis of extracts from COS7 cells, treated with UV (30mins), using Tyrosinase antibody A00326.
Protein Target Info & Infographic
Gene/Protein Information For TYR (Source: Uniprot.org, NCBI)
Gene Name
TYR
Full Name
Tyrosinase
Weight
60393 MW
Superfamily
tyrosinase family
Alternative Names
Tyrosinase;1.14.18.1;LB24-AB;Monophenol monooxygenase;SK29-AB;Tumor rejection antigen AB;TYR; TYR ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase tyrosinase|LB24-AB|SK29-AB|monophenol monooxygenase|oculocutaneous albinism IA|tumor rejection AB
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TYR, check out the TYR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TYR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Tyrosinase Antibody (A00326)
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