Tyrosinase Antibodies

AND TYR ELISA kits, Tyrosinase Proteins

Many biological assays use antibodies to detect Tyrosinase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tyrosinase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tyrosinase antibodies...

We validate the specificity of these antibodies to Tyrosinase by testing them on tissues known to express TYR positively and negatively. Browse below to find the TYR antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TYR Infographic by Boster Bio

All TYR Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Tyrosinase Antibody

Human

$360
Cat # A00326
100 µl

Anti-Tyrosinase (Melanoma Marker) Monoclonal Antibody

Human

Flow Cytometry, IF, IHC

$486
Cat # M00326
100ug/vial

Anti-Tyrosinase Rabbit Monoclonal Antibody

7 Q&As

Human

IF, IHC, ICC, WB

$370
Cat # M00326-1
100 μl

Tyrosinase Colorimetric Cell-Based ELISA Kit

Human

ELISA

$480
Cat # EKC1583
1 kit, containing one 96-well plate and all necessary reagents

Anti-TYR (R501) Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A00326-2
100ul

Anti-Tyrosinase/TYR Antibody Picoband®

Human

ELISA, WB

$370
Cat # A00326-3
100 μg/vial

TYR Overview

Facts about Tyrosinase.

TYR 3D structure. Source: alphafold

Tyrosinase (TYR)

This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions resulting in melanin production from tyrosine.

In addition to hydroxylating tyrosine to DOPA (3,4- dihydroxyphenylalanine), also catalyzes the oxidation of DOPA into DOPA-quinone, and possibly the oxidation of DHI (5,6- dihydroxyindole) into indole-5,6 quinone. .

Gene Information

Human
Gene Name:	TYR
Uniprot:	P14679
Entrez:	7299

Family

Belongs to:

tyrosinase family

Alternative Names

CMM8; EC 1.14.18.1; LB24-AB; Monophenol monooxygenase; OCA1A; OCAIA; SHEP3; SK29-AB; Tumor rejection antigen AB; tyrosinase (oculocutaneous albinism IA); tyrosinase

Molecular Weight

Mass (kDA):
60.393 kDA

Genomic Context


Human

Location:	11q14.3
Sequence:	11; NC_000011.10 (89177565..89295759)

Subcellular Localizations

Melanosome membrane; Single-pass type I membrane protein. Melanosome. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.