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Product Info Summary
| SKU: | A07575 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Trophinin Antibody
SKU/Catalog Number
A07575
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Trophinin Antibody (Catalog # A07575). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Trophinin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Trophinin Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07575)
Host
Rabbit
Contents
Trophinin antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Trophinin antibody was raised against a 16 amino acid peptide near the amino terminus of human Trophinin. The immunogen is located within amino acids 390 - 440 of Trophinin.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Trophinin antibody is human, mouse and rat reactive. Multiple isoforms of Trophinin are known to exist.
Reactive Species
A07575 is reactive to TRO in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
143716 MW
Background of Trophinin
Trophinin, also known as TRO or MAGED3, is an apical cell adhesion molecule that is implicated in the initial attachment during the process of embryo implantation and functions by mediating cell adhesion between trophoblastic and endometrial epithelial cells (1,2). Trophinin is a membrane protein expressed in chorionic villi trophoblasts and in maternal endometrial epithelial cells in an implantation-dependent manner and interacts with Bystin and Tastin, facilitating cell adhesion and embryo implantation (3,4). The induction of Trophinin expression may be a useful method for improving implantation rates and can be a potential diagnostic factor and biomarker for human cancer (4,5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07575 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Trophinin antibody can be used for detection of Trophinin by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry at 10 μg/ml.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Trophinin in rat liver tissue lysate with Trophinin antibody at 1 μg/ml.
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Immunohistochemistry of TROPHININ in mouse liver tissue with TROPHININ antibody at 10 μg/ml.
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Immunofluorescence of Trophinin in mouse liver tissue with Trophinin antibody at 20 μg/ml.
Red: Trophinin Antibody (A07575)
Blue: DAPI staining
Protein Target Info & Infographic
Gene/Protein Information For TRO (Source: Uniprot.org, NCBI)
Gene Name
TRO
Full Name
Trophinin
Weight
143716 MW
Alternative Names
TRO, MAGE-d3, MAGED3 TRO MAGE-d3, MAGED3 trophinin trophinin|MAGE superfamily protein|MAGE-D3 |magphinin|melanoma , family D, 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TRO, check out the TRO Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TRO: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Trophinin Antibody (A07575)
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