Trophinin Antibodies

AND TRO ELISA kits, Trophinin Proteins

Many biological assays use antibodies to detect Trophinin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Trophinin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Trophinin antibodies...

We validate the specificity of these antibodies to Trophinin by testing them on tissues known to express TRO positively and negatively. Browse below to find the TRO antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRO Infographic by Boster Bio

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Anti-Trophinin Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A07575
0.1 mg

TRO Overview

Facts about Trophinin.

TRO 3D structure. Source: alphafold

Trophinin (TRO)

Could be involved with bystin and tastin in a cell adhesion molecule complex which mediates a first attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly accountable for homophilic cell adhesion.

Gene Information

Human
Gene Name:	TRO
Uniprot:	Q12816
Entrez:	7216

Family

Belongs to:

No superfamily

Alternative Names

KIAA1114; MAGE Superfamily Protein; MAGE-D3 Antigen; MAGED3; MAGE-d3; magphinin; Melanoma Antigen, Family D, 3; trophinin

Molecular Weight

Mass (kDA):
143.716 kDA

Genomic Context


Human

Location:	Xp11.21
Sequence:	X; NC_000023.11 (54920563..54931436)

Tissue Specificity

Strong expression at implantation sites. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. Also found in macrophages.

Diseases

Tissue Adhesions
Malignant Neoplasms
Neoplasms
Endometrial Polyp
Insulin Resistance
Femur Head Necrosis
Bone Necrosis
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Pain
Atherosclerosis
Graves Disease
Cell Invasion

Chest Pain
Thyroid Associated Opthalmopathies
Pulmonary Embolism
Lymphoma
Mammary Neoplasms
Acidosis
Tumor Angiogenesis

Interacting Proteins

BYSL

Pathways

Cell Adhesion
Embryo Implantation
Cell Cycle
Cell Death
Cell Proliferation
Angiogenesis
Transport
Homophilic Cell Adhesion
Cell Growth
Pathogenesis
Cell Activation
Cell Cycle Arrest
Localization

Secretion
Protein Phosphorylation
Reflex
Translation
Induction Of Apoptosis
Rna Interference
Excretion

PTMs

Phosphorylation
Cleavage
Oxidation
Hydroxylation

Biotinylation
Reduction
Deamination
Dephosphorylation

Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRO

References

PMID: 7758945 by Fukuda M.N., et al. Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation.

PMID: 23092983 by Nava C., et al. Analysis of the chromosome X exome in patients with autism spectrum disorders identified novel candidate genes, including TMLHE.