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TREM1 Antibodies
AND TREM1 ELISA kits, TREM1 Proteins
Many biological assays use antibodies to detect TREM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TREM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TREM1 antibodies...
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TREM1 Infographic by Boster Bio
All TREM1 Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$499
Cat # EK0845
96 wells/kit, with removable strips.
Cat # EK0845
96 wells/kit, with removable strips.
Anti-TREM1 Antibody Picoband®
1 Citations
Human
Flow Cytometry, IHC, ICC, WB
$370
Cat # A02135-1
100 μg/vial
Cat # A02135-1
100 μg/vial
Human TREM-1 ELISA Kit PicoKine®
1 Citations 12 Q&As
Human
ELISA
$499
Cat # EK0844
96 wells/kit, with removable strips.
Cat # EK0844
96 wells/kit, with removable strips.
TREM1 Overview
Facts about Triggering receptor expressed on myeloid cells 1.
Triggering receptor expressed on myeloid cells 1 (TREM1)
Stimulates neutrophil and monocyte-mediated inflammatory reactions. Triggers launch of pro-inflammatory chemokines and cytokines, as well as enhanced surface expression of cell activation markers.
Amplifier of inflammatory reactions that are triggered by bacterial and fungal infections and is a critical mediator of septic shock. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TREM1 |
| Uniprot: | Q9NP99 |
| Entrez: | 54210 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD354 antigen; CD354; TREM1; TREM-1; TREM-1Triggering receptor expressed on monocytes 1; triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1
Molecular Weight
Mass (kDA):
26.387 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.1 |
| Sequence: | 6; NC_000006.12 (41267385..41286745, complement) |
Tissue Specificity
Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes.
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Diseases
- Systemic Infection
- Inflammation
- Inflammatory Response
- Pneumonia
- Infective Disorder
- Septic Shock
- Bacterial Infections
- Severe Sepsis
- Pneumonia, Bacterial
- Systemic Inflammatory Response Syndrome
- Pneumonia, Ventilator-associated
- Porphyria Cutanea Tarda
- Community-acquired Infections
Pathways
- Inflammatory Response
- Secretion
- Pathogenesis
- Immune Response
- Phagocytosis
- Cytokine Production
- Innate Immune Response
- Cell Activation
- Acute Inflammatory Response
- Neutrophil Degranulation
- Cell Maturation
- Osteoclast Differentiation
- Leukocyte Activation
PTMs
- Phosphorylation
- Carboxylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TREM1
bosterbio.com/bosterbio-gene-info-cards/TREM1
References
PMID: 10799849 by Bouchon A., et al. Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes.
PMID: 11922939 by Gingras M.-C., et al. TREM-1, MDL-1, and DAP12 expression is associated with a mature stage of myeloid development.
2 Publications of Boster TREM1 Antibodies & ELISA Kits
- PubMed ID: 10.3389/fimmu.2021.766178, TREM1 Regulates Neuroinflammatory Injury by Modulate Proinflammatory Subtype Tra...
- PubMed ID: 26648110, Identification of Genes Associated with Smad3-dependent Renal Injury by RNA-seq-...
*More publications can be found for each product on its corresponding product page