Gamma-1-syntrophin Antibodies

AND SNTG1 ELISA kits, Gamma-1-syntrophin Proteins

Many biological assays use antibodies to detect Gamma-1-syntrophin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gamma-1-syntrophin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gamma-1-syntrophin antibodies...

We validate the specificity of these antibodies to Gamma-1-syntrophin by testing them on tissues known to express SNTG1 positively and negatively. Browse below to find the SNTG1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SNTG1 Infographic by Boster Bio

All SNTG1 Products

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Specificity

Applications

Price

Anti-SNTG1 Mouse Monoclonal Antibody [Clone ID: OTI3G10]

Human, Mouse, Rat

IF, WB

$523
Cat # M12103
100 µl

SNTG1 (NM_018967) Human Over-expression Lysate

Human

$628
Cat # LS054212
100 µg

SNTG1 Overview

Facts about Gamma-1-syntrophin.

SNTG1 3D structure. Source: alphafold

Gamma-1-syntrophin (SNTG1)

Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity).

May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation. .

Gene Information

Human
Gene Name:	SNTG1
Uniprot:	Q9NSN8
Entrez:	54212

Family

Belongs to:

syntrophin family

Alternative Names

G1SYNsyntrophin-4; gamma-1-syntrophin; gamma1-syntrophin; SYN4syntrophin 4; syntrophin, gamma 1; Syntrophin-4

Molecular Weight

Mass (kDA):
57.969 kDA

Genomic Context


Human

Location:	8q11.21
Sequence:	8; NC_000008.11 (49909796..50796692)

Tissue Specificity

Brain specific. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia. No expression in muscle cells.

Subcellular Localizations

Cytoplasm, cytoskeleton. Nucleus. Mainly cytoplasmic and weakly nuclear.

Diseases

Malignant Neoplasms
Neoplasms
Muscular Dystrophy
Adenocarcinoma
Neuroblastoma
Lung Neoplasms
Neurodegenerative Disorders
Muscular Dystrophy, Duchenne
Chromosome Inversion
Malignant Neoplasm Of Lung
Dystrophy
Feline Urological Syndrome

Fibrosis
Brain Diseases
Scoliosis, Unspecified
Calcinosis
Basal Ganglia Diseases
Fahr's Syndrome (disorder)

Pathways

Localization
Eye Development
Rna Interference
Response To Paclitaxel

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNTG1

References

PMID: 10747910 by Piluso G., et al. Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells.

PMID: 11352924 by Hogan A., et al. Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions.