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Product Info Summary
| SKU: | A09397 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-TRBP1 TARBP1 Antibody
SKU/Catalog Number
A09397
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-TRBP1 TARBP1 Antibody (Catalog # A09397). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
TRBP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-TRBP1 TARBP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09397)
Host
Rabbit
Contents
TRBP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TRBP1 antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRBP1. The immunogen is located within amino acids 1310 - 1360 of TRBP1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
NKX2-6 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-6 are known to exist; this antibody will detect both isoforms
Reactive Species
A09397 is reactive to TARBP1 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
181675 MW
Background of TARBP1
The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1α (EF-1α), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A09397 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TRBP1 antibody can be used for detection of TRBP1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TRBP1 in 3T3 cell lysate with TRBP1 antibody at (A) 1 and (B) 2 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TARBP1 (Source: Uniprot.org, NCBI)
Gene Name
TARBP1
Full Name
Probable methyltransferase TARBP1
Weight
181675 MW
Superfamily
class IV-like SAM-binding methyltransferase superfamily
Alternative Names
TRM3, TRP185, TRP-185, TRM3, Probable methyltransferase TARBP1, TAR RNA-binding protein 1 TARBP1 TRM3, TRMT3, TRP-185, TRP185 TAR (HIV-1) RNA binding protein 1 probable methyltransferase TARBP1|TAR (HIV) RNA-binding protein 1|TAR RNA loop binding protein|TAR RNA-binding protein 1|TAR RNA-binding protein of 185 kDa|tRNA methyltransferase 3 homolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TARBP1, check out the TARBP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TARBP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TRBP1 TARBP1 Antibody (A09397)
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