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Product Info Summary
| SKU: | A04966-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Transmembrane protein 107 TMEM107 Antibody
SKU/Catalog Number
A04966-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Transmembrane protein 107 TMEM107 Antibody (Catalog # A04966-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
TMEM107antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Transmembrane protein 107 TMEM107 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04966-1)
Host
Rabbit
Contents
TMEM107 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107. The immunogen is located within amino acids 20 - 70 of TMEM107 .
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
TMEM107 antibody is human specific. At least two isoforms of TMEM107 are known to exist.
Reactive Species
A04966-1 is reactive to TMEM107 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
15503 MW
Background of Tmem107
Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and BRCA1 (1,2). TMEM107 is required for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with Gli2 and Gli3 to pattern ventral and intermediate neuronal cell types (1,3). TMEM107 is also a strong candidate gene for central areolar choroidal dystrophy (CACD) (1-3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04966-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TMEM107 antibody can be used for detection of TMEM107 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TMEM107 in THP-1 cell lysate with TMEM107 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of TMEM107 in human lymph node tissue with TMEM107 antibody at 5 μg/mL.
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Immunofluorescence of TMEM107 in human lymph node tissue with TMEM107 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TMEM107 (Source: Uniprot.org, NCBI)
Gene Name
TMEM107
Full Name
Transmembrane protein 107
Weight
15503 MW
Alternative Names
GRVS638, PRO1268, Transmembrane protein 107
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TMEM107, check out the TMEM107 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TMEM107: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Transmembrane protein 107 TMEM107 Antibody (A04966-1)
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