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Product Info Summary
| SKU: | A16224 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Transmembrane protein 106A TMEM106A Antibody
SKU/Catalog Number
A16224
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Transmembrane protein 106A TMEM106A Antibody (Catalog # A16224). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
TMEM106A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Transmembrane protein 106A TMEM106A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A16224)
Host
Rabbit
Contents
TMEM106A Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TMEM106A antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human TMEM106A. The immunogen is located within the first 50 amino acids of TMEM106A.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
NKX2-4 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-4 are known to exist; this antibody will detect both isoforms.
Reactive Species
A16224 is reactive to TMEM106A in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
28920 MW
Background of TMEM106A
Transmembrane protein 106A (TMEM106A) is a single-pass transmembrane protein that is closely related to TMEM106B, a protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual roles of TMEM106A and TMEM106B are still undetermined; however, as TMEM106B is involved in FTLD, it is possible that TMEM106A may also be a risk factor for FTLD.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A16224 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TMEM106A antibody can be used for detection of TMEM106A by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TMEM106A in A-20 cell lysate with TMEM106A antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of TMEM106A in mouse brain tissue with TMEM106A antibody at 5 μg/mL.
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Immunofluorescence of TMEM106A in mouse brain tissue with TMEM106A antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TMEM106A (Source: Uniprot.org, NCBI)
Gene Name
TMEM106A
Full Name
Transmembrane protein 106A
Weight
28920 MW
Superfamily
TMEM106 family
Alternative Names
Transmembrane protein 106A TMEM106A transmembrane protein 106A transmembrane protein 106A
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TMEM106A, check out the TMEM106A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TMEM106A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Transmembrane protein 106A TMEM106A Antibody (A16224)
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