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Product Info Summary
| SKU: | A02777-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Translin TSN Antibody
SKU/Catalog Number
A02777-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Translin TSN Antibody (Catalog # A02777-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Translin antibody can be stored at 4 °C, stable for one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Translin TSN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02777-1)
Host
Rabbit
Contents
Translin Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Translin antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human Translin. The immunogen is located within the last 50 amino acids of Translin.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of Translin are known to exist; this antibody will detect both.
Reactive Species
A02777-1 is reactive to TSN in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
26183 MW
Background of Translin
Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02777-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Translin antibody can be used for detection of Translin by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Translin in rat lung tissue lysate with Translin antibody at (A) 0.5 and (B) 1 μg/mL
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Immunohistochemistry of Translin in human lung tissue with Translin antibody at 5 μg/mL.
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Immunofluorescence of Translin in human lung tissue with Translin antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TSN (Source: Uniprot.org, NCBI)
Gene Name
TSN
Full Name
Translin
Weight
26183 MW
Superfamily
translin family
Alternative Names
C3PO, RCHF1, TBRBP, TRSLN, BCLF-1, REHF-1, Translin, Component 3 of promoter of RISC, C3PO TSN BCLF-1, C3PO, RCHF1, REHF-1, TBRBP, TRSLN translin translin|component 3 of promoter of RISC|recombination hotspot associated factor|recombination hotspot-binding protein|testis brain-RNA binding protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TSN, check out the TSN Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TSN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Translin TSN Antibody (A02777-1)
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