Product Info Summary
SKU: | A00466-2 |
---|---|
Size: | 100µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IF, IHC |
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Product info
Product Name
Anti-TRAIL (human) TNFSF10 Antibody
View all TRAIL/TNFSF10 Antibodies
SKU/Catalog Number
A00466-2
Size
100µl
Form
Liquid. In PBS containing 0.02% sodium azide.
Description
Boster Bio Anti-TRAIL (human) TNFSF10 Antibody catalog # A00466-2. Tested in IF, IHC applications. This antibody reacts with Human.
Storage & Handling
+4°C
Cite This Product
Anti-TRAIL (human) TNFSF10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00466-2)
Host
Rabbit
Contents
Liquid. In PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant human soluble TRAIL (aa 95-281) .
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00466-2 is reactive to TNFSF10 in Human
Reconstitution
Calculated molecular weight
55628 MW
Background of TRAIL/TNFSF10
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00466-2 is guaranteed for IF, IHC Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Optimal conditions must be determined individually for each application.
Validation Images & Assay Conditions
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Figure 1: Schematic structure of the immunogen.
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Figure 2: Detection of recombinant human TRAIL (Prod. No. ALX-522-003
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Figure 3: Immunostaining of HEK 293T cells transfected with a expression plasmid coding for human TRAIL (left panels), or mock transfected (right panel).Method: 3 days after transfection of cells as indicated, cells were fixed with 4% formaldehyde or acetone for 5 min. at RT. Slides were blocked with IgG, and incubated for 1 hour with PAb to TRAIL (Prod. No. A00466-2) at a dilution of
Protein Target Info & Infographic
Gene/Protein Information For TNFSF10 (Source: Uniprot.org, NCBI)
Gene Name
TNFSF10
Full Name
Tumor necrosis factor ligand superfamily member 10
Weight
55628 MW
Superfamily
tumor necrosis factor family
Alternative Names
Cytochrome P450 2C9;1.14.14.- TNFSF10 APO2L, Apo-2L, CD253, TL2, TNLG6A, TRAIL TNF superfamily member 10 tumor necrosis factor ligand superfamily member 10|Apo-2 ligand|TNF-related apoptosis inducing ligand TRAIL|chemokine tumor necrosis factor ligand superfamily member 10|tumor necrosis factor (ligand) family, member 10|tumor necrosis factor (ligand) superfamily, member 10|tumor necrosis factor apoptosis-inducing ligand splice variant delta|tumor necrosis factor ligand 6A|tumor necrosis factor superfamily member 10
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TNFSF10, check out the TNFSF10 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TNFSF10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TRAIL (human) TNFSF10 Antibody (A00466-2)
Hello CJ!
A00466-2 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
AAV-iRFP labelling of human mesenchymal stem cells for near-infrared fluorescence imaging
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