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Product Info Summary
| SKU: | PA2208 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Interferon regulatory factor 5 IRF5 Antibody Picoband®
SKU/Catalog Number
PA2208
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Interferon regulatory factor 5 IRF5 Antibody catalog # PA2208. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Interferon regulatory factor 5 IRF5 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2208)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human IRF5, identical to the related rat sequence, and different from the related mouse sequence by two amino acids.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2208 is reactive to IRF5 in Human, Mouse, Rat
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
53 kDa
Calculated molecular weight
56044 MW
Background of IRF5
Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA2208 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Positive Control
WB: Human Placenta Tissue, Rat Thymus Tissue, Rat Kidney Tissue, Rat Ovary Tissue,
Validation Images & Assay Conditions
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Anti-IRF5 antibody, PA2208, Western blotting
Lane 1: Human Placenta Tissue Lysate
Lane 2: Rat Thymus Tissue Lysate
Lane 3: Rat Kidney Tissue Lysate
Lane 4: Rat Ovary Tissue Lysate
Protein Target Info & Infographic
Gene/Protein Information For IRF5 (Source: Uniprot.org, NCBI)
Gene Name
IRF5
Full Name
Interferon regulatory factor 5
Weight
56044 MW
Superfamily
IRF family
Alternative Names
Interferon regulatory factor 5;IRF-5;IRF5; IRF5 SLEB10 interferon regulatory factor 5 interferon regulatory factor 5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IRF5, check out the IRF5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IRF5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Interferon regulatory factor 5 IRF5 Antibody Picoband® (PA2208)
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