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Product Info Summary
| SKU: | A33174 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-Toll-like receptor 11 TLR11 Antibody
SKU/Catalog Number
A33174
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Toll-like receptor 11 TLR11 Antibody (Catalog # A33174). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Mouse.
Storage & Handling
TLR11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Toll-like receptor 11 TLR11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A33174)
Host
Rabbit
Contents
TLR11 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of mouse TLR11. The immunogen is located within the last 50 amino acids of TLR11.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of HDGFRP2 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other HDGFRP family members
Reactive Species
A33174 is reactive to TLR11 in Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
105873 MW
Background of Tlr11
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A33174 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
TLR11 antibody can be used for detection of TLR11 by Western blot at 0.5 to 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of TLR11 in RAW264.7 cell lysates with TLR11 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunocytochemical staining of RAW264.7 cells using TLR11 antibody at 2 μg/mL.
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Immunofluorescence of TLR11 in Raw264.7 cells with TLR11 antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For TLR11 (Source: Uniprot.org, NCBI)
Gene Name
TLR11
Full Name
Toll-like receptor 11
Weight
105873 MW
Superfamily
Toll-like receptor family
Alternative Names
Gm287, Gm287, Toll-like receptor 11 Tlr11|Gm287|toll-like receptor 11|toll-like receptor 11|toll-like receptor 12
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TLR11, check out the TLR11 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TLR11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Toll-like receptor 11 TLR11 Antibody (A33174)
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