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Key=type_id, value=simple
Key=sku, value=PB9823
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2015-12-31 20:06:40
Key=updated_at, value=2024-09-26 00:46:58
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-TAP1 Antibody Picoband®
Key=cj_search_index
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Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
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Key=featured, value=No
Key=featured_image, value=Yes
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Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Rabbit
Key=quantity_and_stock_status
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1369
Key=yoast_content_score, value=60
Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-TAP1 Antibody Picoband® | Bosterbio
Key=meta_description, value=Boster Bio Anti-TAP1 Antibody Picoband® catalog # PB9823. Tested in IHC, WB applications. This antibody reacts with Human. Supplied as 100μg/vial in Lyophilized form antibody.
Key=image, value=/p/b/pb9823-1.jpg
Key=small_image, value=/p/b/pb9823-1.jpg
Key=thumbnail, value=/p/b/pb9823-1.jpg
Key=url_key, value=anti-tap1-picoband-trade-antibody-pb9823-boster
Key=url_path, value=anti-tap1-picoband-trade-antibody-pb9823-boster
Key=options_container, value=Product Info Column
Key=image_label, value=Anti- TAP1 Picoband antibody, PB9823, Western blotting
All lanes: Anti TAP1 (PB9823) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: HUT Whole Cell Lysate at 40ug
Lane 3: SW620 Whole Cell Lysate at 40ug
Predicted bind size: 8
Key=small_image_label, value=Anti- TAP1 Picoband antibody, PB9823, Western blotting
All lanes: Anti TAP1 (PB9823) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: HUT Whole Cell Lysate at 40ug
Lane 3: SW620 Whole Cell Lysate at 40ug
Predicted bind size: 8
Key=thumbnail_label, value=Anti- TAP1 Picoband antibody, PB9823, Western blotting
All lanes: Anti TAP1 (PB9823) at 0.5ug/ml
Lane 1: HELA Whole Cell Lysate at 40ug
Lane 2: HUT Whole Cell Lysate at 40ug
Lane 3: SW620 Whole Cell Lysate at 40ug
Predicted bind size: 8
Key=msrp_display_actual_price_type, value=
Key=gift_message_available, value=No
Key=size, value=100 μg/vial
Key=protein_name, value=Antigen peptide transporter 1
Key=gene_full_name, value=Antigen peptide transporter 1
Key=uniprot_id, value=Q03518
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=sensitivity
Key=applications, value=IHC, WB
Key=reactivity, value=Human
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Key=predicted_reactivity
Key=source_company, value=Boster PB9823
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=87218 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Adapters, Signal Transduction, Transmembrane
Key=clonality, value=Polyclonal
Key=swatch_image, value=/e/k/ek0447.png
Key=rating_value, value=100
Key=review_count, value=3
Key=phospho_site
Key=mp_exclude_sitemap, value=Yes
Key=yoast_focus_keyword, value=CD68 antibody
Key=yoast_facebook_image, value=/p/b/pb9800-cd19-primary-antibodies-wb-testing-1.jpg
Key=yoast_twitter_image, value=/p/b/pb9800-cd19-primary-antibodies-wb-testing-1.jpg
Key=cj_related_products, value=Antigen Processing And Presentation:A02941-1|A07927^Peptide Transport:A05292-1^Tumor Escape:A02821-3|M00109-2|M00109-3
Key=description, value=Boster Bio Anti-TAP1 Antibody Picoband® catalog # PB9823. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-TAP1 Antibody Picoband® catalog # PB9823. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-TAP1 Antibody Picoband®
Key=contents, value=Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Key=background, value=Transporter associated with Antigen Processing 1 is a protein that in humans is encoded by the TAP1 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. And ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Key=gene_name, value=TAP1
Key=synonyms, value=Antigen peptide transporter 1;APT1;ATP-binding cassette sub-family B member 2;Peptide supply factor 1;Peptide transporter PSF1;PSF-1;Peptide transporter TAP1;Peptide transporter involved in antigen processing 1;Really interesting new gene 4 protein;TAP1;ABCB2, PSF1, RING4, Y3;
Key=application_details, value=Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Key=subcellular_localization, value= Endoplasmic reticulum membrane; Multi-pass membrane protein. The transmembrane segments seem to form a pore in the membrane.
Key=tissue_specificity, value= Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung. .
Key=application_notes, value=Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 20930|sc 11458|sc 11465|sc 11464|sc 376796|sc 11458 R
Key=immunogen, value=A synthetic peptide corresponding to a sequence in the middle region of human TAP1, different from the related mouse sequence by eight amino acids, and from the related rat sequence by nine amino acids.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=87 kDa
Key=custom_attribute_2, value=WB: HELA Whole Cell, HUT Whole Cell, SW620 Whole Cell
IHC: human intestinal cancer tissue
Key=protein_function, value= Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. Inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association. Expression of TAP1 is down-regulated by human Epstein-Barr virus vIL-10 protein, thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules.
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