Anti-TAK1 Map3k7 Antibody

Product Name

Anti-TAK1 Map3k7 Antibody

View all TAK1 Antibodies

SKU/Catalog Number

A01458

Size

100μg/vial

Form

Liquid

Description

Boster Bio Anti-TAK1 Map3k7 Antibody catalog # A01458. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store vial at 4°C prior to opening. This product is stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, mix with an equal volume of glycerol, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of opening.

Cite This Product

Anti-TAK1 Map3k7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01458)

Host

Rabbit

Contents

Each vial contains 50% glycerol and 0.09% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthetic peptide corresponding to a portion of mouse TAK1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01458 is reactive to Map3k7 in Human, Mouse, Rat

Reconstitution

Observed Molecular Weight

42 kDa

Calculated molecular weight

64228 MW

Background of TAK1

Mitogen-activated protein kinase kinase kinase 7, also known as TAK1, is an enzyme that in humans is encoded by the MAP3K7 gene. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A01458 is guaranteed for IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

User needs to optimize the dilution ratio for this antibody.

Validation Images & Assay Conditions

Gene/Protein Information For Map3k7 (Source: Uniprot.org, NCBI)

Alternative Names

Mitogen-activated protein kinase kinase kinase 7;2.7.11.25;Transforming growth factor-beta-activated kinase 1;TGF-beta-activated kinase 1;Map3k7;Tak1; MAP3K7 CSCF, FMD2, MEKK7, TAK1, TGF1a mitogen-activated protein kinase kinase kinase 7 mitogen-activated protein kinase kinase kinase 7|TGF-beta activated kinase 1|transforming growth factor-beta-activated kinase 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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