Anti-TAF1/Kat4 Antibody

Product Name

Anti-TAF1/Kat4 Antibody

View all KAT4/TBP Associated Factor 1 Antibodies

SKU/Catalog Number

A02151-1

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-TAF1/Kat4 Antibody (Catalog # A02151-1). Tested in IHC applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-TAF1/Kat4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02151-1)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human TAF1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02151-1 is reactive to TAF1 in Human, Mouse

Reconstitution

Calculated molecular weight

212677 MW

Background of KAT4/TBP Associated Factor 1

Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.

Sekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991).
Ruppert S., Nature 362:175-179(1993).
Nolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A02151-1 is guaranteed for IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

Gene/Protein Information For TAF1 (Source: Uniprot.org, NCBI)

Alternative Names

Transcription initiation factor TFIID subunit 1;2.3.1.48;2.7.11.1;Cell cycle gene 1 protein;TBP-associated factor 250 kDa;p250;Transcription initiation factor TFIID 250 kDa subunit;TAF (II)250;TAFII-250;TAFII250;TAF1;BA2R, CCG1, CCGS, TAF2A; TAF1 BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, MRXS33, N-TAF1, NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP TATA-box binding protein associated factor 1 transcription initiation factor TFIID subunit 1|TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa|TBP-associated factor 250 kDa|cell cycle gene 1 protein|cell cycle, G1 phase defect|complementation of cell cycle block, G1-to-S|transcription factor TFIID p250 polypeptide

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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