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- Table of Contents
Facts about Transcription initiation factor TFIID subunit 1.
Phosphorylates TP53 on'Thr-55' which leads to MDM2- mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues.
Human | |
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Gene Name: | TAF1 |
Uniprot: | P21675 |
Entrez: | 6872 |
Belongs to: |
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TAF1 family |
250kDa; BA2Rdystonia 3 (with Parkinsonism); CCG1TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 250kD; CCGS; Cell cycle gene 1 protein; cell cycle, G1 phase defect; complementation of cell cycle block, G1-to-S; DYT3/TAF1; EC 2.7.11; EC 2.7.11.1; KAT4; NSCL2; OF; P250; TAF(II)250; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF2AN-TAF1; TAFII-250; TAFII250DYT3; TBP-associated factor 250 kDa; transcription factor TFIID p250 polypeptide; Transcription initiation factor TFIID 250 kDa subunit; transcription initiation factor TFIID subunit 1; XDP
Mass (kDA):
212.677 kDA
Human | |
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Location: | Xq13.1 |
Sequence: | X; NC_000023.11 (71366220..71530525) |
Nucleus.
PMID: 2038334 by Sekiguchi T., et al. The human CCG1 gene, essential for progression of the G1 phase, encodes a 210-kilodalton nuclear DNA-binding protein.
PMID: 3169001 by Sekiguchi T., et al. Molecular cloning of the cDNA of human X chromosomal gene (CCG1) which complements the temperature-sensitive G1 mutants, tsBN462 and ts13, of the BHK cell line.