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Product Info Summary
| SKU: | A01937-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-SRSF protein kinase 1 SRPK1 Antibody
SKU/Catalog Number
A01937-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SRSF protein kinase 1 SRPK1 Antibody (Catalog # A01937-1). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SRPK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-SRSF protein kinase 1 SRPK1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01937-1)
Host
Rabbit
Contents
SRPK1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SRPK1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human SRPK1. The immunogen is located within the first 50 amino acids of SRPK1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SRPK1 antibody is human, mouse and rat reactive. Multiple isoforms of SRPK1 are known to exist; this antibody will detect all except isoforms b and e. SRPK1 antibody is predicted to not cross-react with SRPK2.
Reactive Species
A01937-1 is reactive to SRPK1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
74325 MW
Background of SRPK1
SRPK1 and SRPK2, two Arginine/serine-rich (SR) protein-specific kinases constitute control circuits to regulate both constitutive and alternative pre-mRNA splicing and coordinate splicing with transcription in cells (1). They are highly specific for the phosphorylation of these RS proteins, and highly expressed in testis (1,2). SRPK1 plays a role in the condensation of sperm chromatin and controls the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis (3,4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01937-1 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SRPK1 antibody can be used for the detection of SRPK1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry at 5 μg/ml.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SRPK1 in mouse heart tissue lysate with SRPK1 antibody at 1 μg/ml.
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Immunohistochemistry of SRPK1 in human testis tissue with SRPK1 antibody at 5 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For SRPK1 (Source: Uniprot.org, NCBI)
Gene Name
SRPK1
Full Name
SRSF protein kinase 1
Weight
74325 MW
Superfamily
protein kinase superfamily
Alternative Names
SRSF protein kinase 1, Serine/arginine-rich protein-specific kinase 1, Serine/threonine-protein kinase SRPK1, SFRSK1, SR-protein-specific kinase 1 SRPK1 SFRSK1 SRSF protein kinase 1 SRSF protein kinase 1|SFRS protein kinase 1|SR-protein-specific kinase 1|serine/arginine-rich splicing factor kinase 1|serine/threonine-protein kinase SRPK1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SRPK1, check out the SRPK1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SRPK1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SRSF protein kinase 1 SRPK1 Antibody (A01937-1)
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