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Product Info Summary
| SKU: | A06268 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SRPX2 Antibody
SKU/Catalog Number
A06268
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SRPX2 Antibody (Catalog # A06268). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SRPX2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SRPX2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06268)
Host
Rabbit
Contents
SRPX2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SRPX2 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SRPX2. The immunogen is located within the first 50 amino acids of SRPX2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
DNAJC13 antibody is human and mouse reactive. At least two siforms of DNAJC13 are known to exist; this antibody will detect both isoforms. DNAJC13 antibody is predicted to not cross-react with other DNAJC family members.
Reactive Species
A06268 is reactive to SRPX2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
52972 MW
Background of SRPX2
Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06268 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SRPX2 antibody can be used for detection of SRPX2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SRPX2 in human lung tissue lysate with SRPX2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of SRPX2 in rat lung tissue with SRPX2 antibody at 5 μg/mL.
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Immunofluorescence of SRPX2 in human lung tissue with SRPX2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SRPX2 (Source: Uniprot.org, NCBI)
Gene Name
SRPX2
Full Name
Sushi repeat-containing protein SRPX2
Weight
52972 MW
Alternative Names
BPP, CBPS, PMGX, RESDX, SRPUL, Sushi repeat-containing protein SRPX2, Sushi-repeat protein upregulated in leukemia SRPX2 BPP, CBPS, PMGX, RESDX, SRPUL sushi repeat containing protein X-linked 2 sushi repeat-containing protein SRPX2|sushi-repeat protein up-regulated in leukemia|sushi-repeat protein upregulated in leukemia
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SRPX2, check out the SRPX2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SRPX2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SRPX2 Antibody (A06268)
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