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Product Info Summary
| SKU: | A04982 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SKI2W SKIV2L Antibody
SKU/Catalog Number
A04982
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SKI2W SKIV2L Antibody (Catalog # A04982). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SKI2W antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-SKI2W SKIV2L Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04982)
Host
Rabbit
Contents
SKI2W antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SKI2W antibody was raised against a 16 amino acid peptide near the amino terminus of human SKI2W. The immunogen is located within amino acids 60 - 110 of SKI2W.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SKI2W antibody is human, mouse and rat reactive. At least two isoforms of SKI2W are known to exist; this antibody will detect both isoforms.
Reactive Species
A04982 is reactive to SKIV2L in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
137755 MW
Background of SKIV2L
SKI2W (SKIV2L, Helicase-like protein), a DEVH-box protein, is a component of the SKI complex which is involved in the regulation of translation and RNA turnover (1,2). SKI2W is a nucleolar and cytoplasmic protein that has a putative RNA helicase domain (2). The potential roles of Ski2W on the clearance of degraded nuclear and cytoplasmic RNA raised their possibilities as susceptibility genes of systemic lupus erythematosus (3,4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04982 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SKI2W antibody can be used for detection of SKI2W by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SKI2W in mouse stomach tissue lysate with SKI2W antibody at 1 μg/ml.
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Immunohistochemistry of SKI2W in human stomach tissue with SKI2W antibody at 5 μg/ml.
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Immunofluorescence of SKI2W in human stomach tissue with SKI2W antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For SKIV2L (Source: Uniprot.org, NCBI)
Gene Name
SKIV2L
Full Name
Helicase SKI2W
Weight
137755 MW
Superfamily
helicase family
Alternative Names
Superkiller viralicidic activity 2-like, DDX13, Helicase-like protein, Helicase SKI2W, HLP, SKI2, SKIV2, SKIV2L SKIV2L 170A, DDX13, HLP, SKI2, SKI2W, SKIV21, THES2, SKIV2L Ski2 like RNA helicase helicase SKI2W|SKI2 homolog, superkiller viralicidic activity 2-like|helicase-like protein|superkiller viralicidic activity 2-like
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SKIV2L, check out the SKIV2L Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SKIV2L: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SKI2W SKIV2L Antibody (A04982)
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