Helicase SKI2W Antibodies

AND SKIV2L ELISA kits, Helicase SKI2W Proteins

Many biological assays use antibodies to detect Helicase SKI2W, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Helicase SKI2W in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Helicase SKI2W antibodies...

We validate the specificity of these antibodies to Helicase SKI2W by testing them on tissues known to express SKIV2L positively and negatively. Browse below to find the SKIV2L antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SKIV2L Infographic by Boster Bio

All SKIV2L Products

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Specificity

Applications

Price

Anti-SKI2W SKIV2L Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A04982
0.1 mg

Helicase SKI2W (SKIV2L) (NM_006929) Human Over-expression Lysate

Human

$628
Cat # LS006499
100 µg

SKIV2L Overview

Facts about Helicase SKI2W.

SKIV2L 3D structure. Source: alphafold

Helicase SKI2W (SKIV2L)

Helicase; has ATPase activity. Component of the SKI complex that's thought to participate in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C).

Gene Information

Human
Gene Name:	SKIV2L
Uniprot:	Q15477
Entrez:	6499

Family

Belongs to:

helicase family

Alternative Names

170A; DDX13helicase SKI2W; EC 3.6.1; Helicase-like protein; HLPEC 3.6.4.-; SKI2; SKI2Wsuperkiller viralicidic activity 2 (S. cerevisiae homolog)-like; SKIV2; superkiller viralicidic activity 2-like (S. cerevisiae); W

Molecular Weight

Mass (kDA):
137.755 kDA

Genomic Context


Human

Location:	6p21.33
Sequence:	6; NC_000006.12 (31959157..31969852)

Subcellular Localizations

Nucleus. Cytoplasm.

Diseases

Age Related Macular Degeneration
Lupus Erythematosus, Systemic
Dysequilibrium Syndrome
Autoimmune Diseases
Autoimmune Reaction
Sclerosis
Choroid Diseases
Wooly Hair
Infantile Diarrhea
Peripheral Vascular Diseases
Diarrhea
L1 Acute Lymphoblastic Leukemia

Childhood Leukemia
Multiple Sclerosis
Malignant Paraganglionic Neoplasm
Tissue Adhesions
Acute Lymphocytic Leukemia
Blind Vision

Pathways

Translation
Dna Replication
Pathogenesis
Cell Adhesion
Ribosome Biogenesis
Rna Surveillance
Reverse Transcription
Dna Repair

Regulation Of Gene Expression
Regulation Of Translation
Rna Splicing

PTMs

Methylation

Research Areas

Lipid and Metabolism
Unfolded Protein Response
Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SKIV2L

References

PMID: 7759100 by Lee S.-G., et al. Identification and characterization of a human cDNA homologous to yeast SKI2.

PMID: 7610041 by Dangel A.W., et al. Human helicase gene SKI2W in the HLA class III region exhibits striking structural similarities to the yeast antiviral gene SKI2 and to the human gene KIAA0052: emergence of a new gene family.