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Product Info Summary
| SKU: | A12146 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-SGSM2 Antibody
SKU/Catalog Number
A12146
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SGSM2 Antibody (Catalog # A12146). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SGSM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SGSM2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12146)
Host
Rabbit
Contents
SGSM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SGSM2 antibody was raised against an 18 amino acid synthetic peptide near the center of human SGSM2. The immunogen is located within amino acids 650 - 700 of SGSM2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of SGSM2 are known to exist. SGSM2 antibody is predicted to not cross react with other SGSM family proteins.
Reactive Species
A12146 is reactive to SGSM2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
113285 MW
Background of SGSM2
Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12146 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SGSM2 antibody can be used for detection of SGSM2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SGSM2 in human cerebellum tissue lysate with SGSM2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide
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Immunofluorescence of SGSM2 in human brain tissue with SGSM2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SGSM2 (Source: Uniprot.org, NCBI)
Gene Name
SGSM2
Full Name
Small G protein signaling modulator 2
Weight
113285 MW
Superfamily
RUTBC family
Alternative Names
RUTBC1, KIAA0397, RUTBC1, Small G protein signaling modulator 2, RUN and TBC1 domain-containing protein 1 SGSM2 RUTBC1 small G protein signaling modulator 2 small G protein signaling modulator 2|RUN and TBC1 domain containing 1|small G protein signaling modulator 2 protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SGSM2, check out the SGSM2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SGSM2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SGSM2 Antibody (A12146)
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