Product Info Summary
SKU: | A07461 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-PPP3CC Antibody
SKU/Catalog Number
A07461
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PPP3CC Antibody catalog # A07461. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PPP3CC Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07461)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human GABA T-3
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07461 is reactive to PPP3CC in Human, Mouse, Rat
Applications
A07461 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
58129 MW
Background of PPP3CC
Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.
Nakajima D., DNA Res. 9:99-106(2002).
Olsen J.V., Cell 127:635-648(2006).
Hirosawa M., DNA Res. 6:329-336(1999).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
Validation Images & Assay Conditions
![a07461 anti ppp3cc antibody wb testing 1 a07461 anti ppp3cc antibody wb testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a07461-anti-ppp3cc-antibody-wb-testing-1.jpg)
Click image to see more details
Figure 1. Western blotting validation for Anti-PPP3CC Antibody A07461
Western blot analysis of extracts of various cellsProtein Target Info & Infographic
Gene/Protein Information For PPP3CC (Source: Uniprot.org, NCBI)
Gene Name
PPP3CC
Full Name
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
Weight
58129 MW
Superfamily
PPP phosphatase family
Alternative Names
Calcineurin, testis-specific catalytic subunit; Calmodulin-dependent calcineurin A subunit gamma isoform; CALNA3CAM-PRP catalytic subunit; CNA3; EC 3.1.3.16; PP2Bgamma; protein phosphatase 2B, catalytic subunit, gamma isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform(calcineurin A gamma); protein phosphatase 3, catalytic subunit, gamma isozyme; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform PPP3CC CALNA3, CNA3, PP2Bgamma protein phosphatase 3 catalytic subunit gamma serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform|CAM-PRP catalytic subunit|calcineurin, testis-specific catalytic subunit|protein phosphatase 3, catalytic subunit, gamma isozyme
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PPP3CC, check out the PPP3CC Infographic
![PPP3CC infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PPP3CC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PPP3CC Antibody (A07461)
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No publications found for A07461
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