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Product Info Summary
| SKU: | A02904 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-S1PR2 Antibody
View all S1P2/EDG-5/S1PR2 Antibodies
SKU/Catalog Number
A02904
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-S1PR2 Antibody (Catalog # A02904). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
S1PR2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-S1PR2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02904)
Host
Rabbit
Contents
S1PR2 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
S1PR2 antibody was raised against an 16 amino acid peptide near the carboxy terminus of human S1PR2. The immunogen is located within amino acids 270 - 320 of S1PR2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
S1PR2 antibody is human, mouse and rat reactive.
Reactive Species
A02904 is reactive to S1PR2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
38867 MW
Background of S1P2/EDG-5/S1PR2
The Sphingosine 1-phosphate receptor 2 (S1PR2) protein was initially identified as G-protein coupled receptor thought to be involved in development (1) and was found to mediate sphingosine 1-phosphate (SPP)-induced cell rounding and neurite retraction (2). S1PR2 and the related protein S1PR3 (also known as EDG3) are also thought to mediate the SPP-induced cell proliferation, survival, and related signaling events (3). S1PR2 has also been found to be key regulator in acute vascular inflammation and may be a novel therapeutic target for vascular disorders (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02904 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
S1PR2 antibody can be used for detection of S1PR2 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry at 10 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of S1PR2 in HeLa cell lysate with S1PR2 antibody at 1 μg/ml.
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Immunohistochemistry of S1PR2 in mouse brain tissue with S1PR2 antibody at 10 μg/ml.
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Immunofluorescence of S1PR2 in mouse brain tissue with S1PR2 antibody at 20 μg/ml.
Red: S1PR2 Antibody (A02904)
Blue: DAPI staining
Protein Target Info & Infographic
Gene/Protein Information For S1PR2 (Source: Uniprot.org, NCBI)
Gene Name
S1PR2
Full Name
Sphingosine 1-phosphate receptor 2
Weight
38867 MW
Superfamily
G-protein coupled receptor 1 family
Alternative Names
Sphingosine 1-phosphate receptor 2, S1P2, AGR16, EDG-5, EDG5, Gpcr13, H218, LPB2 S1PR2 AGR16, DFNB68, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2 sphingosine-1-phosphate receptor 2 sphingosine 1-phosphate receptor 2|CTD-2369P2.2|S1P receptor 2|S1P receptor EDG5|S1P receptor Edg-5|deafness, autosomal recessive 68|endothelial differentiation G-protein coupled receptor 5|endothelial differentiation, sphingolipid G-protein-coupled receptor, 5|sphingosine 1-phosphate receptor Edg-5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on S1PR2, check out the S1PR2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for S1PR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-S1PR2 Antibody (A02904)
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