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- Table of Contents
Facts about Sphingosine 1-phosphate receptor 2.
When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis (PubMed:10617617). Receptor for the chemokine-like protein FAM19A5 (PubMed:29453251).
Human | |
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Gene Name: | S1PR2 |
Uniprot: | O95136 |
Entrez: | 9294 |
Belongs to: |
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G-protein coupled receptor 1 family |
AGR16; EDG5; EDG-5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; GPCR13; GPCR18; H218; LPB2; S1P receptor 2; S1P receptor EDG5; S1P receptor Edg-5; S1P2; S1PR2; sphingosine 1-phosphate receptor 2; sphingosine 1-phosphate receptor Edg-5; sphingosine-1-phosphate receptor 2
Mass (kDA):
38.867 kDA
Human | |
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Location: | 19p13.2 |
Sequence: | 19; NC_000019.10 (10221433..10231331, complement) |
Cell membrane; Multi-pass membrane protein.
PMID: 10617617 by An S., et al. Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5.
PMID: 26805784 by Santos-Cortez R.L., et al. Autosomal-recessive hearing impairment due to rare missense variants within S1PR2.