Product Info Summary
SKU: | A12655 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-RSRC1 Antibody
SKU/Catalog Number
A12655
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-RSRC1 Antibody (Catalog # A12655). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
RSRC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-RSRC1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12655)
Host
Rabbit
Contents
RSRC1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
RSRC1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human RSRC1. The immunogen is located within the last 50 amino acids of RSRC1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
AP3M1 antibody may cross-react with AP3M2.
Reactive Species
A12655 is reactive to RSRC1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
38677 MW
Background of RSRC1
The arginine/serine-rich coiled-coil 1 protein (RSRC1) was initially identified as a non-snRNP splicing factor that has a role in both the constitutive and alternative splicing of pre-mRNA molecules. In cellular nuclear extracts immunodepleted of RSRC1, the second step of pre-mRNA splicing is blocked; recombinant RSRC1 is able to restore splicing activity. RSRC1 has also been reported to be associated with schizophrenia as well as a unique marker of bone marrow-derived stem cells that also express the cdc34 marker.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12655 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RSRC1 antibody can be used for detection of RSRC1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of RSRC1 in HepG2 cell lysate with RSRC1 antibody at (A) 1 and (B) 2 μg/mL.
Click image to see more details
Immunohistochemistry of RSRC1 in rat liver tissue with RSRC1 antibody at 5 μg/mL.
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Immunofluorescence of RSRC1 in rat liver tissue with RSRC1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For RSRC1 (Source: Uniprot.org, NCBI)
Gene Name
RSRC1
Full Name
Serine/Arginine-related protein 53
Weight
38677 MW
Alternative Names
BM-011, SFRS21, SRrp53, SRRP53, BM-011SRrp53 RSRC1 BM-011, MRT70, SFRS21, SRrp53 arginine and serine rich coiled-coil 1 serine/Arginine-related protein 53|arginine/serine-rich coiled-coil 1|arginine/serine-rich coiled-coil protein 1|splicing factor, arginine/serine-rich 21
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RSRC1, check out the RSRC1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RSRC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-RSRC1 Antibody (A12655)
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