Anti-GTP-binding protein Rit1 RIT1 Antibody

Product Name

Anti-GTP-binding protein Rit1 RIT1 Antibody

View all RIT1 Antibodies

SKU/Catalog Number

A06008

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-GTP-binding protein Rit1 RIT1 Antibody (Catalog # A06008). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GTP-binding protein Rit1 RIT1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06008)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human RIT1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A06008 is reactive to RIT1 in Human

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Calculated molecular weight

25145 MW

Background of RIT1

Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.

Manabu Furukawa, Mol. Cell. Biol., Nov 2000; 20: 8185 - 8197.
Angus Chen, J. Biol. Chem., May 2000; 275: 15432.
Kenneth Wu, Mol. Cell. Biol., Feb 2000; 20: 1382 - 1393.
Kenneth Wu, J. Biol. Chem., Jan 2002; 277: 516 - 527.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A06008 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For RIT1 (Source: Uniprot.org, NCBI)

Alternative Names

GTP-binding protein Rit1;Ras-like protein expressed in many tissues;Ras-like without CAAX protein 1;RIT1;RIBB, RIT, ROC1; RIT1 NS8, RIBB, RIT, ROC1 Ras like without CAAX 1 GTP-binding protein Rit1|GTP-binding protein Roc1|Ric-like, expressed in many tissues|ras-like protein expressed in many tissues|ras-like without CAAX protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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