Anti-Reticulon-4 receptor-like 2 RTN4RL2 Antibody

Product Name

Anti-Reticulon-4 receptor-like 2 RTN4RL2 Antibody

View all NgR2/NgRH1/RTN4RL2 Antibodies

SKU/Catalog Number

A10682

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Reticulon-4 receptor-like 2 RTN4RL2 Antibody (Catalog # A10682). Tested in ELISA, WB applications. This antibody reacts with Human.

Storage & Handling

RTN4RL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Reticulon-4 receptor-like 2 RTN4RL2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10682)

Host

Rabbit

Contents

RTN4RL2 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Rabbit polyclonal RTN4RL2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RTN4RL2. The immunogen is located within amino acids 330 - 380 of RTN4RL2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Three alternatively spliced transcript variants have been observed. RTN4RL2 antibody is predicted to not cross-react with other Nogo receptor-like proteins.

Reactive Species

A10682 is reactive to RTN4RL2 in Human

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

46106 MW

Background of NgR2/NgRH1/RTN4RL2

Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A10682 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

RTN4RL2 antibody can be used for detection of RTN4RL2 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For RTN4RL2 (Source: Uniprot.org, NCBI)

Alternative Names

NgR2, NGRH1, NGRL3, Reticulon-4 receptor-like 2, Nogo receptor-like 3, NgR2 Rtn4rl2|Ng, Ngr, Ngr2, Ngrh1, Ngrl3|reticulon 4 receptor-like 2|reticulon-4 receptor-like 2|nogo receptor-like 3|nogo-66 receptor homolog 1|nogo-66 receptor-related protein 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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