Anti-Ras-related protein Rab-31 RAB31 Antibody

Product Name

Anti-Ras-related protein Rab-31 RAB31 Antibody

View all RAB31 Antibodies

SKU/Catalog Number

A05883

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Ras-related protein Rab-31 RAB31 Antibody (Catalog # A05883). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Ras-related protein Rab-31 RAB31 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05883)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human RAB31.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05883 is reactive to RAB31 in Human, Mouse, Rat

Reconstitution

Calculated molecular weight

21569 MW

Background of RAB31

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Chen D., Gene 174:129-134(1996) [PubMed: 8863739].
Bao X.,Eur. J. Biochem. 269:259-271(2002) [PubMed: 11784320].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].<

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A05883 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For RAB31 (Source: Uniprot.org, NCBI)

Alternative Names

Ras-related protein Rab-31;Ras-related protein Rab-22B;RAB31;RAB22B; RAB31 Rab22B RAB31, member RAS oncogene family ras-related protein Rab-31|ras-related protein Rab-22B

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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