This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Ras-related protein Rab-31.
Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes.
Human | |
---|---|
Gene Name: | RAB31 |
Uniprot: | Q13636 |
Entrez: | 11031 |
Belongs to: |
---|
small GTPase superfamily |
Rab22B; RAB31, member RAS oncogene family; Ras-related protein Rab-22B; ras-related protein Rab-31
Mass (kDA):
21.569 kDA
Human | |
---|---|
Location: | 18p11.22 |
Sequence: | 18; NC_000018.10 (9708187..9862551) |
Highest expression in placenta and brain with lower levels in heart and lung. Not detected in liver, skeletal muscle, kidney or pancreas.
Golgi apparatus, trans-Golgi network. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Rapidly recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
PMID: 8863739 by Chen D., et al. Molecular cloning of two novel rab genes from human melanocytes.
PMID: 11784320 by Bao X., et al. Molecular cloning, bacterial expression and properties of Rab31 and Rab32.