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Product Info Summary
| SKU: | A02707 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-PRRT2 Antibody
SKU/Catalog Number
A02707
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PRRT2 Antibody (Catalog # A02707). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PRRT2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-PRRT2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02707)
Host
Rabbit
Contents
PRRT2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PRRT2 antibody was raised against a 18 amino acid peptide near the center of human PRRT2 . The immunogen is located within amino acids 180 - 230 of PRRT2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of PRRT2 are known to exist.
Reactive Species
A02707 is reactive to PRRT2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
34945 MW
Background of Prrt2
The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02707 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PRRT2 Antibody can be used for detection of PRRT2 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PRRT2 in mouse brain tissue lysate with PRRT2 antibody at 1 μg/mL.
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Immunohistochemistry of PRRT2 in rat brain tissue with PRRT2 antibody at 2.5 μg/ml.
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Immunofluorescence of PRRT2 in rat brain tissue with PRRT2 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For PRRT2 (Source: Uniprot.org, NCBI)
Gene Name
PRRT2
Full Name
Proline-rich transmembrane protein 2
Weight
34945 MW
Superfamily
CD225/Dispanin family
Alternative Names
PKC, EKD1, ICCA, BFIC2, BFIS2, DSPB3, DYT10, FICCA, IFITMD1, Proline-rich transmembrane protein 2, Dispanin subfamily B member 3 Prrt2|1500031I19Rik, AI195361, DSPB3|proline-rich transmembrane protein 2|proline-rich transmembrane protein 2|dispanin subfamily B member 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PRRT2, check out the PRRT2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PRRT2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PRRT2 Antibody (A02707)
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