Anti-PRL-3 Antibody

Product Name

Anti-PRL-3 Antibody

View all PRL-3/PTP4A3 Antibodies

SKU/Catalog Number

A03108

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-PRL-3 Antibody (Catalog # A03108). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PRL-3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03108)

Host

Rabbit

Contents

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Peptide sequence around aa. 161-166 (K-D-P-H-T) derived from Human PTP4A3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03108 is reactive to PTP4A3 in Human, Mouse, Rat

Applications

A03108 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

19535 MW

Background of PRL-3/PTP4A3

Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.

Matter W.F. et.al. Biochem. Biophys. Res. Commun. 283:1061-1068(2001)
Wang J.et.al. J. Biol. Chem. 277:46659-46668(2002)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Predicted MW: 22kd
Western blotting: 1:500~1:1000

Validation Images & Assay Conditions

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Western blot analysis of extract from LX-2 cells transfected with PRL-3 using PRL-3 antibody A03108.

Gene/Protein Information For PTP4A3 (Source: Uniprot.org, NCBI)

Alternative Names

PRL3; PRL-3; PRL3EC 3.1.3.48; PRL-3potentially prenylated protein tyrosine phosphatase; PRL-Rprotein tyrosine phosphatase type IVA 3; protein tyrosine phosphatase type IVA, member 3; Protein-tyrosine phosphatase 4a3; Protein-tyrosine phosphatase of regenerating liver 3; PTP4A3 PTP4A3 PRL-3, PRL-R, PRL3 protein tyrosine phosphatase 4A3 protein tyrosine phosphatase type IVA 3|phosphatase of regenerating liver 3|potentially prenylated protein tyrosine phosphatase|protein tyrosine phosphatase type IVA, member 3|protein-tyrosine phosphatase of regenerating liver 3

For more info on PTP4A3, check out the PTP4A3 Infographic

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In this infographic, you will see the following information for PTP4A3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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