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Product Info Summary
| SKU: | M00138-1 |
|---|---|
| Size: | 100 μl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | Flow Cytometry, WB |
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Product info
Product Name
Anti-Presenilin 1 Monoclonal Antibody
View all Presenilin-1 Antibodies
SKU/Catalog Number
M00138-1
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-Presenilin 1 Monoclonal Antibody catalog # M00138-1. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Presenilin 1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00138-1)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
AECD-16
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human Presenilin 1 Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) . Requires the other members of the gamma-secretase complex to have a protease activity.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00138-1 is reactive to PSEN1 in Human, Mouse, Rat
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Observed Molecular Weight
25 kDa
Calculated molecular weight
40076 MW
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00138-1 is guaranteed for Flow Cytometry, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
FC 1:10
Positive Control
WB: Jurkat cell
Validation Images & Assay Conditions
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Western blot analysis of Presenilin 1 expression in Jurkat cell lysate.
Protein Target Info & Infographic
Gene/Protein Information For PSEN1 (Source: Uniprot.org, NCBI)
Gene Name
PSEN1
Full Name
Presenilin-1
Weight
40076 MW
Superfamily
peptidase A22A family
Alternative Names
Monocyte differentiation antigen CD14 ;Myeloid cell-specific leucine-rich glycoprotein;CD14;Monocyte differentiation antigen CD14, urinary form;Monocyte differentiation antigen CD14, membrane-bound form;CD14; PSEN1 ACNINV3, AD3, FAD, PS-1, PS1, S182 presenilin 1 presenilin-1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PSEN1, check out the PSEN1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PSEN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Presenilin 1 Monoclonal Antibody (M00138-1)
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No publications found for M00138-1
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Customer Q&As
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6 Customer Q&As for Anti-Presenilin 1 Monoclonal Antibody
Question
Would anti-Presenilin 1 Monoclonal antibody M00138-1 work for WB with corpus callosum?
Verified Customer
Verified customer
Asked: 2020-02-21
Answer
According to the expression profile of corpus callosum, PSEN1 is highly expressed in corpus callosum. So, it is likely that anti-Presenilin 1 Monoclonal antibody M00138-1 will work for WB with corpus callosum.
Boster Scientific Support
Answered: 2020-02-21
Question
I was wanting to use your anti-Presenilin 1 Monoclonal antibody for WB for mouse corpus callosum on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for mouse corpus callosum identification?
Verified Customer
Verified customer
Asked: 2020-01-14
Answer
As indicated on the product datasheet, M00138-1 anti-Presenilin 1 Monoclonal antibody has been validated for WB on human, mouse, rat tissues. We have an innovator award program that if you test this antibody and show it works in mouse corpus callosum in IHC-frozen, you can get your next antibody for free.
Boster Scientific Support
Answered: 2020-01-14
Question
Thank you for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for corpus callosum using anti-Presenilin 1 Monoclonal antibody M00138-1. Let me know if you need anything else.
Verified Customer
Verified customer
Asked: 2019-11-19
Answer
Thank you for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2019-11-19
Question
See attached the WB image, lot number and protocol we used for corpus callosum using anti-Presenilin 1 Monoclonal antibody M00138-1. Please let me know if you require anything else.
Verified Customer
Verified customer
Asked: 2018-08-06
Answer
Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2018-08-06
Question
We are currently using anti-Presenilin 1 Monoclonal antibody M00138-1 for rat tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on horse tissues as well?
Verified Customer
Verified customer
Asked: 2018-06-28
Answer
The anti-Presenilin 1 Monoclonal antibody (M00138-1) has not been validated for cross reactivity specifically with horse tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2018-06-28
Question
I am interested in to test anti-Presenilin 1 Monoclonal antibody M00138-1 on mouse corpus callosum for research purposes, then I may be interested in using anti-Presenilin 1 Monoclonal antibody M00138-1 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
Verified Customer
Verified customer
Asked: 2018-05-17
Answer
The products we sell, including anti-Presenilin 1 Monoclonal antibody M00138-1, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2018-05-17
