Anti-PPM1A Picoband® Antibody

PP2C alpha/PPM1A antibody

Boster Bio Anti-PPM1A Picoband® Antibody catalog # A02928-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Info Summary

SKU: A02928-1
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, IHC, WB

Product Name

Anti-PPM1A Picoband® Antibody

View all PP2C alpha/PPM1A Antibodies

SKU/Catalog Number

A02928-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-PPM1A Picoband® Antibody catalog # A02928-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PPM1A Picoband® Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02928-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human PPM1A, identical to the related mouse and rat sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A02928-1 is reactive to PPM1A in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

40 kDa

Calculated molecular weight

79686 MW

Background of PP2C alpha/PPM1A

Protein phosphatase 1A is an enzyme that in humans is encoded by the PPM1A gene. It is mapped to 14q23.1. The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A02928-1 is guaranteed for ELISA, IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human
ELISA, 0.1-0.5μg/ml, -

Positive Control

WB: human Hela whole cell, human HepG2 whole cell, human Jurkat whole cell, human K562 whole cell
IHC: human appendicitis tissue, human gastric cancer tissue, human pancreatic cancer tissue, human rectal cancer tissue

Validation Images & Assay Conditions

Gene/Protein Information For PPM1A (Source: Uniprot.org, NCBI)

Gene Name

PPM1A

Full Name

Protein phosphatase 1A

Weight

79686 MW

Superfamily

PP2C family

Alternative Names

Protein phosphatase 1A; Protein phosphatase 2C isoform alpha; PP2C-alpha; Protein phosphatase IA; PPM1A; PPPM1A PPM1A PP2C-ALPHA, PP2CA, PP2Calpha protein phosphatase, Mg2+/Mn2+ dependent 1A protein phosphatase 1A

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PPM1A, check out the PPM1A Infographic

PPM1A infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PPM1A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02928-1

100μg

$370
A02928-1-10ug

10μg sample (liquid)

$99
A02928-1-Biotin

100 μg Biotin conjugated

$570
A02928-1-Cy3

100 μg Cy3 conjugated

$570
A02928-1-Dylight488

100 μg Dylight488 conjugated

$570
A02928-1-Dylight550

100 μg Dylight550 conjugated

$570
A02928-1-Dylight594

100 μg Dylight594 conjugated

$570
A02928-1-FITC

100 μg FITC conjugated

$570
A02928-1-HRP

100 μg HRP conjugated

$570
A02928-1-APC

100 μg APC conjugated

$670
A02928-1-PE

100 μg PE conjugated

$670
A02928-1-iFluor647

100 μg iFluor647 conjugated

$670
A02928-1-carrier-free

Carrier Free

$370

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A02928-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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