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- Table of Contents
Facts about Protein phosphatase 1A.
Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Human | |
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Gene Name: | PPM1A |
Uniprot: | P35813 |
Entrez: | 5494 |
Belongs to: |
---|
PP2C family |
EC 3.1.3.16; FLJ42306; MGC9201; MMPa-2; MPPa-1; phosphatase 2C alpha; PP2C alpha; Pp2c1; PP2CA; PP2Calpha; PP2C-ALPHA; PPM1A; PPPM1A; protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform; protein phosphatase 1A; protein phosphatase 2C alpha isoform; Protein phosphatase 2C isoform alpha; Protein phosphatase IA; protein phosphatase, Mg2+/Mn2+ dependent, 1A
Mass (kDA):
42.448 kDA
Human | |
---|---|
Location: | 14q23.1 |
Sequence: | 14; NC_000014.9 (60245750..60299087) |
Nucleus. Cytoplasm, cytosol. Membrane; Lipid-anchor. Weakly associates at the membrane and N-myristoylation mediates the membrane localization.
You can optimize your experiments with the Boster Bio using a few tips. Read the troubleshooting guides in the Boster Bio to learn how to optimize your experiments and get better results. No experiment is perfect and every researcher runs into trouble at some point. But with the proper controls, you can eliminate many possible sources of error. This guide will help you to identify common troubleshooting issues and prevent them.
A Boster Bio troubleshooting guide is a good place to start when you are running your own experiments. The company's ELISA protocol includes step-by-step instructions to guide you through the process. This guide serves as primer or quick reference for the entire procedure. It also includes tips for optimizing the experiment and addressing common questions. Listed below are a few tips and tricks that may help you get the best results with your Boster ELISA.
Developing the perfect staining method is critical for a successful IHC. Boster Bio's guide explains step-by-step techniques for optimal staining, including a detailed illustrated protocol and recommended reagents. The guide also covers the process of preparing different types of preserved tissues for optimal staining. It also outlines the best techniques for preparing tissue samples. For example, the guide includes an extensive procedure for preparing a variety of tissue samples. A quality sample is the key to good staining results.
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PMID: 1311954 by Mann D.J., et al. Mammalian protein serine/threonine phosphatase 2C: cDNA cloning and comparative analysis of amino acid sequences.
PMID: 9707433 by Takekawa M., et al. Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways.