Anti-Phospho-TOB1 (S164) Antibody

Product Name

Anti-Phospho-TOB1 (S164) Antibody

View all TOB1 Antibodies

SKU/Catalog Number

P04119

Size

100μl

Form

Liquid

Description

Boster Bio Anti-Phospho-TOB1 (S164) Antibody catalog # P04119. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Phospho-TOB1 (S164) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # P04119)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human TOB1 around the phosphorylation site of S164.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

P04119 is reactive to TOB1 in Human, Mouse, Rat

Applications

P04119 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

52 kDa

Calculated molecular weight

38155 MW

Background of TOB1

MEK5 (also known as MKK5) is a dual specificity serine/threonine protein kinase belonging to the MAP kinase kinase family. MEK5 has been shown to specifically activate ERK5 (Zhou et al., 1995) whereas MEK5 itself is regulated by MEKK3 (Chao et al., 1999). An important link between MEK5 and metastatic prostrate cancer has been demonstrated (Mehta et.al., 2003). Dual phosphorylation of Ser-311 and Thr-315 have been implicated in cell proliferation (Cameron et al., 2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of JK cells using Phospho-TOB1 (S164) Polyclonal antibody.

Gene/Protein Information For TOB1 (Source: Uniprot.org, NCBI)

Alternative Names

APRO6; MGC104792; PIG49; protein Tob1; TOB1; TOBMGC34446; Transducer of erbB-2 1; transducer of ERBB2, 1; TROB; TROB1 TOB1 APRO5, APRO6, PIG49, TOB, TROB, TROB1 transducer of ERBB2, 1 protein Tob1|proliferation-inducing gene 49|transducer of erbB-2 1

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In this infographic, you will see the following information for TOB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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