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Product Info Summary
| SKU: | A08193 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-PACS2 Antibody
SKU/Catalog Number
A08193
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PACS2 Antibody (Catalog # A08193). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PACS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-PACS2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08193)
Host
Rabbit
Contents
PACS2 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
PACS2 antibody was raised against a 17 amino acid peptide near the center of human PACS2. The immunogen is located within amino acids 330 - 380 of PACS2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
PACS2 antibody is human, mouse and rat reactive. At least three isoforms of PACS2 are known to exist; this antibody will detect all three. PACS2 antibody is predicted to not cross-react with PACS1.
Reactive Species
A08193 is reactive to PACS2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
97702 MW
Background of PACS2
PACS2 (phosphofurin acidic cluster sorting protein-2), PACS1L, is an 889 amino acid protein that localizes to both the mitochondrion and the lumen of the endoplasmic reticulum (ER) and belongs to the PACS family (1,2). It is expressed in a broad range of tissues with highest expression in skeletal muscle, brain, heart, testis and pancreas (2,). PACS2 interacts with Polycystin-2 and BID and functions as a sorting protein that regulates mitochondria-ER communication and is thought to be involved in ion channel trafficking, specifically direct cluster-containing ion channels to distinct subcellular compartments (3-5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08193 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PACS2 antibody can be used for detection of PACS2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PACS2 in mouse brain tissue lysate with PACS2 antibody at 1 μg/ml.
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Immunohistochemistry of PACS2 in mouse brain tissue with PACS2 antibody at 5 μg/mL.
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Immunofluorescence of PACS2 in mouse brain tissue with PACS2 antibody at 20 μg/ml.
Red: PACS2 Antibody (A08193)
Blue: DAPI staining
Protein Target Info & Infographic
Gene/Protein Information For PACS2 (Source: Uniprot.org, NCBI)
Gene Name
PACS2
Full Name
Phosphofurin acidic cluster sorting protein 2
Weight
97702 MW
Superfamily
PACS family
Alternative Names
Phosphofurin acidic cluster sorting protein 2, PACS-2, PACS1-like protein, PACS1L PACS2 DEE66, EIEE66, PACS-2, PACS1L phosphofurin acidic cluster sorting protein 2 phosphofurin acidic cluster sorting protein 2|PACS1-like protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PACS2, check out the PACS2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PACS2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PACS2 Antibody (A08193)
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