Anti-Osm Antibody Picoband®

Oncostatin M/OSM antibody

Boster Bio Anti-Osm Antibody Picoband® catalog # A00804-3. Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Info Summary

SKU: A00804-3
Size: 100 µg/vial
Reactive Species: Mouse, Rat
Host: Rabbit
Application: ELISA, WB

Product Name

Anti-Osm Antibody Picoband®

View all Oncostatin M/OSM Antibodies

SKU/Catalog Number

A00804-3

Size

100 µg/vial

Form

Lyophilized

Description

Boster Bio Anti-Osm Antibody Picoband® catalog # A00804-3. Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-Osm Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00804-3)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

IgG

Immunogen

E.coli-derived rat Osm recombinant protein (Position: E55-D158). Rat Osm shares 46% and 71.2% amino acid (aa) sequence identity with human and mouse Osm, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00804-3 is reactive to Osm in Mouse, Rat

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Observed Molecular Weight

27 kDa

Calculated molecular weight

52588 MW

Background of Oncostatin M/OSM

OSM (ONCOSTATIN M) is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. This gene encodes a growth regulator which inhibits the proliferation of a number of tumor cell lines. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is mapped on 22q12.2. OSM has the ability to inhibit the growth of human A375 melanoma cells but not normal human fibroblasts. Treatment with recombinant OSM leads to the inhibition of proliferation and changes in cellular morphology of a number of tumor cell lines derived from a wide variety of tissue types. OSM also has the ability to inhibit the proliferation of murine M1 myeloid leukemic cells and can induce their differentiation into macrophage-like cells, a function shared by LIF, CSF3, and IL6. The direction of gene transcription was telomeric to centromeric, with the OSM gene located upstream of the LIF gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A00804-3 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 μg/ml, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, Rat

Positive Control

WB: rat testis tissue, rat kidney tissue, rat C6 whole cell, mouse tetis tissue, mouse kidney tissue, mouse lung tissue, mouse RAW2647 whole cell

Validation Images & Assay Conditions

Gene/Protein Information For Osm (Source: Uniprot.org, NCBI)

Gene Name

Osm

Full Name

Oncostatin-M

Weight

52588 MW

Superfamily

LIF/OSM family

Alternative Names

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody OSM oncostatin M oncostatin-M

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Osm, check out the Osm Infographic

Osm infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Osm: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00804-3

100μg

$370
A00804-3-10ug

10μg sample (liquid)

$99
A00804-3-Biotin

100 μg Biotin conjugated

$570
A00804-3-Cy3

100 μg Cy3 conjugated

$570
A00804-3-Dylight488

100 μg Dylight488 conjugated

$570
A00804-3-Dylight550

100 μg Dylight550 conjugated

$570
A00804-3-Dylight594

100 μg Dylight594 conjugated

$570
A00804-3-FITC

100 μg FITC conjugated

$570
A00804-3-HRP

100 μg HRP conjugated

$570
A00804-3-APC

100 μg APC conjugated

$670
A00804-3-PE

100 μg PE conjugated

$670
A00804-3-iFluor647

100 μg iFluor647 conjugated

$670
A00804-3-carrier-free

Carrier Free

$370

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A00804-3
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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