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Product Info Summary
| SKU: | A03724 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-NUP107 Antibody
View all Nucleoporin 107 Antibodies
SKU/Catalog Number
A03724
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-NUP107 Antibody (Catalog # A03724). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
NUP107 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-NUP107 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03724)
Host
Rabbit
Contents
NUP107 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
NUP107 antibody was raised against a 20 amino acid synthetic peptide from near the center of human NUP107. The immunogen is located within amino acids 370 - 420 of NUP107.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
WAPL antibody is human, mouse and rat reactive. At least four isoforms of WAPL are known to exist.
Reactive Species
A03724 is reactive to NUP107 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
106374 MW
Background of Nucleoporin 107
The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03724 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
NUP107 antibody can be used for detection of NUP107 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 10 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of NUP107 in A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 μg/mL.
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Immunocytochemistry of NUP107 in A549 cells with NUP107 antibody at 10 μg/mL.
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Immunofluorescence of NUP107 in A549 cells with NUP107 antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For NUP107 (Source: Uniprot.org, NCBI)
Gene Name
NUP107
Full Name
Nuclear pore complex protein Nup107
Weight
106374 MW
Superfamily
nucleoporin Nup84/Nup107 family
Alternative Names
NUP84, Nuclear pore complex protein Nup107, 107 kDa nucleoporin NUP107 NPHS11, NUP84, ODG6, ODG6; GAMOS7 nucleoporin 107 nuclear pore complex protein Nup107|nucleoporin 107kDa
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NUP107, check out the NUP107 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NUP107: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NUP107 Antibody (A03724)
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