Product Info Summary
SKU: | A00485-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-NOTCH3 Antibody
SKU/Catalog Number
A00485-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-NOTCH3 Antibody catalog # A00485-1. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-NOTCH3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00485-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human XIAP around the phosphorylation site of S87.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00485-1 is reactive to NOTCH3 in Human, Mouse, Rat
Applications
A00485-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
243631 MW
Background of Notch-3
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP) is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules. FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-NOTCH3 Antibody A00485-1
Western blot (WB) analysis of NOTCH3 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysate
Lane2:sp2/0 whole cell lysate
Lane3:PC12 whole cell lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For NOTCH3 (Source: Uniprot.org, NCBI)
Gene Name
NOTCH3
Full Name
Neurogenic locus notch homolog protein 3
Weight
243631 MW
Superfamily
NOTCH family
Alternative Names
CADASIL; CASILneurogenic locus notch homolog protein 3; Notch (Drosophila) homolog 3; notch 3Notch homolog 3 (Drosophila); Notch homolog 3; Notch3; Notch-3 NOTCH3 CADASIL, CADASIL1, CASIL, IMF2, LMNS notch receptor 3 neurogenic locus notch homolog protein 3|Notch homolog 3|notch 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NOTCH3, check out the NOTCH3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NOTCH3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NOTCH3 Antibody (A00485-1)
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No publications found for A00485-1
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