Anti-NASP Antibody

Product Name

Anti-NASP Antibody

View all NASP Antibodies

SKU/Catalog Number

A05383

Size

100ul

Form

Liquid

Description

Boster Bio Anti-NASP Antibody catalog # A05383. Tested in WB,IHC,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NASP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05383)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human AHNK protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05383 is reactive to NASP in Human, Mouse, Rat

Applications

A05383 is guaranteed for IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

111 kDa

Calculated molecular weight

85238 MW

Background of NASP

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

Beebe S.J., Mol. Endocrinol. 4:465-475(1990).
Gregory S.G., Nature 441:315-321(2006).
Wu K.-J., Oncogene 21:7872-7882(2002).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-NASP Antibody A05383

Western blot analysis of extracts of various cell lines

Gene/Protein Information For NASP (Source: Uniprot.org, NCBI)

Alternative Names

DKFZp547F162; FLB7527; FLJ31599; FLJ35510; histone H1-binding protein; MGC19722; MGC20372; MGC2297; nuclear autoantigenic sperm protein (histone-binding); nuclear autoantigenic sperm protein; PRO1999 NASP FLB7527, HMDRA1, PRO1999 nuclear autoantigenic sperm protein nuclear autoantigenic sperm protein|NASP histone chaperone|histone H1-binding protein|nuclear autoantigenic sperm protein (histone-binding)

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In this infographic, you will see the following information for NASP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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